The 49ers opened the season with two road games in which they walloped the Pittsburgh Steelers 22-7 and dispatched the Los Angeles Rams 30-23 in a divisional matchup. In their home opener, they’ll face the Giants, who began their season by falling to the Dallas Cowboys in an embarrassing 40-0 home loss before they traveled to Phoenix to get past the Arizona Cardinals 30-28 in Week 2.
According to DraftKings Sportsbook, the 49ers are favored by 10.5 points.
Here are our picks for Thursday night’s game. Be sure to cast your vote, too — and discuss the game in the comments!
Arrowhead Pride readers pick
READER RECORD: 22-10-0
Which team wins Giants (1-1) at 49ers (2-0)?
This poll is closed
AP Staff Record
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