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Week 5 of the NFL season kicks off with a big NFC West battle that should be a great game: the Los Angeles Rams (3-1) on the road against the Seattle Seahawks (2-2) on Thursday Night Football.
Sunday’s action begins at 8:30 a.m. Arrowhead Time, as the New York Jets (1-3) are at the Atlanta Falcons (1-3) from London’s Tottenham Hotspur Stadium. It’s the first game of the league’s 2021 International Series.
In a huge AFC matchup, the Kansas City Chiefs will be at home to face the Buffalo Bills on Sunday Night Football. Kickoff is scheduled for 7:20 p.m. Arrowhead Time. The Chiefs are favored by 2.5 points according to DraftKings Sportsbook.
Elsewhere in the AFC West, the Pittsburgh Steelers (1-3) will host the Denver Broncos (3-1) in Sunday’s early-afternoon games — while in the late games, the Chicago Bears (2-2) will be in Sin City to play the Las Vegas Raiders (3-1) and the Los Angeles Chargers (3-1) will host the Cleveland Browns (3-1) in another of Sunday’s big matchups.
In other noteworthy early-afternoon games, the Green Bay Packers (3-1) travel to Ohio to play the Cincinnati Bengals (3-1) and the Washington Football Team (2-2) hosts the New Orleans Saints (2-2). The late-afternoon slate will feature an NFC East matchup with the New York Giants (1-3) at the Dallas Cowboys (3-1) and an NFC West battle in which the Arizona Cardinals (4-0) will host the San Francisco 49ers (2-2).
Then for Monday Night Football, the Indianapolis Colts (1-3) will return to their city of origin to play the Baltimore Ravens (3-1).
Here are our picks for this weekend’s games. Be sure to cast your vote, too!
Arrowhead Pride readers pick
READER RECORD: 38-25-1
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Which team wins Rams (3-1) at Seahawks (2-2)?
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Which team wins Jets (1-3) at Falcons (1-3)?
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Which team wins Lions (0-4) at Vikings (1-3)?
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Which team wins Dolphins (1-3) at Buccaneers (3-1)?
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Which team wins Saints (2-2) at Washington (2-2)?
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Which team wins Titans (2-2) at Jaguars (0-4)?
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Which team wins Broncos (3-1) at Steelers (1-3)?
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Which team wins Packers (3-1) at Bengals (3-1)?
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Which team wins Patriots (1-3) at Texans (1-3)?
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Which team wins Eagles (1-3) at Panthers (3-1)?
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Which team wins Bears (2-2) at Raiders (3-1)?
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Which team wins Browns (3-1) at Chargers (3-1)?
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Which team wins Giants (1-3) at Cowboys (3-1)?
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Which team wins 49ers (2-2) at Cardinals (4-0)?
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Which team wins Colts (1-3) at Ravens (3-1)?
Reader Record by Week
| Predictions | W-L-T |
| Week 1 picks | 8-7-1 |
| Week 2 picks | 10-6-0 |
| Week 3 picks | 10-6-0 |
| Week 4 picks | 10-6-0 |
| Total | 38-25-1 |
AP Staff Record
| Rnk | LW | Staffer | W | L | T | Pct |
| 1 | 3 | Stephen Serda | 43 | 21 | 0 | 0.6719 |
| 1 | 5 | Matt Stagner | 43 | 21 | 0 | 0.6719 |
| 3 | 6 | Ron Kopp Jr. | 42 | 22 | 0 | 0.6563 |
| 4 | 3 | Kramer Sansone | 38 | 20 | 0 | 0.6552 |
| 5 | 6 | Bryan Stewart | 41 | 23 | 0 | 0.6406 |
| 5 | 6 | Jared Sapp | 41 | 23 | 0 | 0.6406 |
| 7 | 1 | Talon Graff | 40 | 24 | 0 | 0.6250 |
| 7 | 10 | Ethan Willinger | 40 | 24 | 0 | 0.6250 |
| 7 | 12 | Pete Sweeney | 40 | 24 | 0 | 0.6250 |
| 10 | 9 | Mark Gunnels | 19 | 13 | 0 | 0.5938 |
| 11 | 10 | Rocky Magaña | 37 | 27 | 0 | 0.5781 |
| 12 | 12 | John Dixon | 36 | 28 | 0 | 0.5625 |
In Week 4, Pete Sweeney, Ron Kopp and Matt Stagner all went 12-4-0 straight up to lead the AP staff. John Dixon was 12-4-0 against the spread, while Rocky Magaña and Matt were both 10-6-0 on over/under. Overall, Matt led the staff with a 32-16-0 record in Week 4, while John and Ron both came in at 31-17-0. Among 357 Tallysight experts who picked games in Week 4, all three finished in the top 20.
Odds/lines subject to change. T&Cs apply. See draftkings.com/sportsbook for details.
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