West was ruled questionable with a hamstring injury and didn't practice this week. It was reported early Sunday morning by ESPN that he would be out but there were other reports that he was trying to tough it out. But he's inactive so he won't be playing.
West will be replaced by Spencer Ware in the backfield along with Knile Davis. Expect Ware to get the bulk of the carries with Davis filling in as needed. For fantasy purposes, Ware is your workhorse.
De'Anthony Thomas could've also had some time in the backfield but he's inactive as well.
Here are the inactive Chiefs:
G Ben Grubbs, DE Allen Bailey, LB Dee Ford, WR De'Anthony Thomas, RB Charcandrick West, QB Aaron Murray, DL David King.