Lions Vs. 49ers: Sunday Night Football Schedule Week 2 Kicks Off

DETROIT - OCTOBER 16: Jim Harbaugh head coach of the San Francisco 49ers argues with Jim Schwartz of the Detroit Lions during the NFL game at Ford Field on October 16, 2011 in Detroit, Michigan. The 49ers defeated the Lions 25-19. (Photo by Leon Halip/Getty Images)

The Detroit Lions take on the San Francisco 49ers in the Week 2 edition of Sunday Night Football. You can watch the game on NBC or stream it online at NBC Sports. Game time is 8:20 p.m. EST.

You can follow along with Lions fans at Pride of Detroit and 49ers fans at Niners Nation.

What's your final score prediction for tonight? How's your fantasy team look so far?

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