The Kansas City Chiefs and San Diego Chargers are the final game of the first week of the 2010 regular season.
ESPN's panel of experts have weighed in and just two pick the Chiefs to win.
Considering the two games from last year, the Chargers are the safe bet here.
Picking the Chiefs: Adam Schefter and Ron Jaworski
Picking against the Chiefs: Eric Allen, Mike Golic, Merrill Hoge, Chris Mortensen, Mark Schlereth, Seth Wickersham, AccuScore (computerized) and Pick 'Em (fans).
Get used to folks picking against the Chiefs. From an outsider's perspective, this is still a four-win team.
The Chiefs are 4.5 point underdogs on Monday Night football.
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